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Common allergic reactions include skin manifestations like itching, erythema, and urticaria upon contact with hops or hops-containing products. Inhalation of hop dust during brewing or consumption of products containing hops can lead to respiratory symptoms, such as rhinitis, conjunctivitis, and asthma exacerbation.

It's kinda hard to explain and it gets covered in great detail in the first two games. But basically Ys is an ancient land that once was part of the world, but is now basically a floating island.

Music. The first two games were composed by Yuzo Koshiro, Mieko Ishikawa, and Hideya Nagata, whereas Mieko Ishikawa handled the soundtrack for Ys III.